Genome Biol. 2009;10(8):234. Epub 2009 Aug 11.

Virus-mediated mRNA decay by hyperadenylation.

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Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.

Abstract

Degradation of cellular mRNAs during Kaposi's sarcoma-associated herpesvirus infection is associated with hyperadenylation of transcripts and a relocalization of cytoplasmic poly(A)-binding proteins to the nucleus.

PMID:: 19678916; [PubMed - indexed for MEDLINE]
PMCID: PMC2745759

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MeSH Terms

Substances

RNA, Messenger

Grant Support

AI63434/AI/NIAID NIH HHS/United States

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