J Biol. 2009;8(5):48. Epub 2009 May 28.

Can modular analysis identify disease-associated candidate genes for therapeutics?

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Department of Medicine, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Solna, Stockholm, Sweden. jesper.tegner@ki.se

Abstract

Complex diseases such as allergy change gene expression in several cell types and tissues. Benson and colleagues have now shown, in a paper in BMC Systems Biology, that this complexity can be studied effectively using an integrated experimental and computational modular analysis. Their strategy revealed a core of allergy-associated genes of potential therapeutic value.

PMID:: 19519937; [PubMed - indexed for MEDLINE]
PMCID: PMC2736663

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