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Department of Physiology, University of Turku, Finland.
The ability of oral isolates of Streptococcus mutans, Streptococcus sanguis, Bacillus cereus and Candida albicans to metabolize 17 beta-estradiol was analyzed by thin-layer chromatography using 4-14C-estradiol as the substrate. All test microorganisms metabolized 17 beta-estradiol. Estrone was the main metabolic product, except for B. cereus, which converted 17 beta-estradiol mainly to unidentified, more polar metabolites. S. sanguis and B. cereus had the most active metabolism but S. mutans and C. albicans were also active.
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