Arthritis Res Ther. 2008;10(5):120. Epub 2008 Oct 17.

Serum urate, menopause, and postmenopausal hormone use: from eminence to evidence-based medicine.

Abstract

The relationship between serum urate, menopause, and aging has not been clearly defined by scientific evidence. In the present issue of Arthritis Research and Therapy, Hak and Choi present a cross-sectional analysis to clarify the effect of menopause and hormone replacement therapy on serum urate in women within the Third National Health and Nutritional Examination Survey. Menopause increased serum urate and hormone replacement therapy significantly decreased serum urate, although the overall level of change was small. The implications of these urate changes on gout and cardiovascular disease outcomes require further study.

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Arthritis Res Ther. 2008;10(5):R116.

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PMCID: PMC2592808

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Uric Acid

MW: 168.11 g/mol

MF: C₅H₄N₄O₃

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