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    J Hematol Oncol. 2008 Oct 17;1:18.

    Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: a case report.

    So BJ, Bekaii-Saab T, Bloomston MA, Patel T.

    Source

    The Ohio State University Medical Center, 395 W, 12th Avenue, Columbus, OH 43210, USA. brian.so@osumc.edu

    Abstract

    Hepatocellular carcinoma is rare, but increasing in prevalence in the United States. Recent studies have shown that sorafenib, a multikinase inhibitor, can reduce tumor progression in patients with this cancer. However, complete remission has not been observed. We report a case of a 78-year old patient with unresectable metastatic hepatocellular carcinoma who had a rapid and complete clinical response following therapy with sorafenib for six months. No evidence of disease recurrence has been noted for 6 months after discontinuation of therapy.

    PMID:
    18928548
    [PubMed - indexed for MEDLINE]
    PMCID: PMC2575202
    Free PMC Article

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