Epigenetics. 2008 Jul-Aug;3(4):188-92. Epub 2008 Jul 29.

Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks.

Source

Molecular Genetics and Evolution Group, ARC Special Research Centre for Molecular Genetics of Development, Research School of Biological Sciences, The Australian National University, Canberra, Australia. maleszka@rsbs.anu.edu.au

Abstract

The discovery of a family of highly conserved DNA cytosine methylases in honey bees and other insects suggests that, like mammals, invertebrates possess a mechanism for storing epigenetic information that controls heritable states of gene expression. Recent data also show that silencing DNA methylation in young larvae mimics the effects of nutrition on early developmental processes that determine the reproductive fate of honey bee females. We evaluate the impact of these findings on future studies of environmentally-driven phenotypic plasticity in social insects, and discuss how they may help in understanding the nutritional basis of epigenetic reprogramming in humans.

PMID:: 18719401; [PubMed - indexed for MEDLINE]

Free full text

Publication Types, MeSH Terms

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

LinkOut - more resources

Full Text Sources

Landes Bioscience

Other Literature Sources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Epigenetic regulation of the honey bee transcriptome: unravelling the nature of methylated genes. [BMC Genomics. 2009]
Epigenetic regulation of the honey bee transcriptome: unravelling the nature of methylated genes.
Foret S, Kucharski R, Pittelkow Y, Lockett GA, Maleszka R. BMC Genomics. 2009 Oct 14; 10:472. Epub 2009 Oct 14.
Nutritional control of reproductive status in honeybees via DNA methylation. [Science. 2008]
Nutritional control of reproductive status in honeybees via DNA methylation.
Kucharski R, Maleszka J, Foret S, Maleszka R. Science. 2008 Mar 28; 319(5871):1827-30. Epub 2008 Mar 13.
Functional CpG methylation system in a social insect. [Science. 2006]
Functional CpG methylation system in a social insect.
Wang Y, Jorda M, Jones PL, Maleszka R, Ling X, Robertson HM, Mizzen CA, Peinado MA, Robinson GE. Science. 2006 Oct 27; 314(5799):645-7.
Review Epigenetic reprogramming in mammalian development. [Science. 2001]
Review Epigenetic reprogramming in mammalian development.
Reik W, Dean W, Walter J. Science. 2001 Aug 10; 293(5532):1089-93.
Review Epigenetic interplay between histone modifications and DNA methylation in gene silencing. [Mutat Res. 2008]
Review Epigenetic interplay between histone modifications and DNA methylation in gene silencing.
Vaissière T, Sawan C, Herceg Z. Mutat Res. 2008 Jul-Aug; 659(1-2):40-8. Epub 2008 Feb 29.

See reviews... See all...

Cited by 12 PubMed Central articles

Aphids: a model for polyphenism and epigenetics. [Genet Res Int. 2012]
Aphids: a model for polyphenism and epigenetics.
Srinivasan DG, Brisson JA. Genet Res Int. 2012; 2012:431531. Epub 2012 Mar 21.
Diet and cell size both affect queen-worker differentiation through DNA methylation in honey bees (Apis mellifera, Apidae). [PLoS One. 2011]
Diet and cell size both affect queen-worker differentiation through DNA methylation in honey bees (Apis mellifera, Apidae).
Shi YY, Huang ZY, Zeng ZJ, Wang ZL, Wu XB, Yan WY. PLoS One. 2011 Apr 26; 6(4):e18808. Epub 2011 Apr 26.
DNA methylation, the early-life social environment and behavioral disorders. [J Neurodev Disord. 2011]
DNA methylation, the early-life social environment and behavioral disorders.
Szyf M. J Neurodev Disord. 2011 Sep; 3(3):238-49. Epub 2011 Mar 11.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Epigenetic integration of environmental and genomic signals in honey bees: the c...
Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks.
Epigenetics. 2008 Jul-Aug ;3(4):188-92. Epub 2008 Jul 29 .

PubMed
Interaction of ring B unsaturated estrogens with estrogen receptors of human end...
Interaction of ring B unsaturated estrogens with estrogen receptors of human endometrium and rat uterus.
Steroids. 1991 Apr ;56(4):201-10.

PubMed
Use of nicotine replacement therapy during pregnancy and stillbirth: a cohort st...
Use of nicotine replacement therapy during pregnancy and stillbirth: a cohort study.
BJOG. 2008 Oct ;115(11):1405-10. Epub 2008 Aug 20 .

PubMed
Cysteine and glutathione concentrations in plasma and bronchoalveolar lavage flu...
Cysteine and glutathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine.
Thorax. 1991 Jan ;46(1):39-42.

PubMed
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful ...
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.
Mamm Genome. 2008 Jun ;19(6):382-9. Epub 2008 Aug 21 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: