Trends Genet. 1991 Jan;7(1):28-33.

RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway.

Source

Department of Molecular Biology, Princeton University, NJ 08544.

Abstract

Ras proteins in budding yeasts initially appeared to regulate initiation of the cell cycle in response to nutrient availability. More recent work, while clarifying the mechanism of Ras-mediated signal transduction, has undermined our notion of the signal Ras transmits. We now suspect that Ras helps to coordinate cellular metabolism and mass accumulation, but what Ras responds to is not clear.

PMID:: 1848378; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Cyclic AMP

Grant Support

CA 41086/CA/NCI NIH HHS/United States

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Review The RAS-adenylate cyclase pathway and cell cycle control in Saccharomyces cerevisiae. [Antonie Van Leeuwenhoek. 1992]
Review The RAS-adenylate cyclase pathway and cell cycle control in Saccharomyces cerevisiae.
Thevelein JM. Antonie Van Leeuwenhoek. 1992 Aug; 62(1-2):109-30.
The glucose-induced CDC25- and RAS-mediated cAMP signal in the yeast Saccharomyces cerevisiae. [Yeast. 1989]
The glucose-induced CDC25- and RAS-mediated cAMP signal in the yeast Saccharomyces cerevisiae.
Thevelein JM, Beullens M, Mbonyi K, Van Aelst L. Yeast. 1989 Apr; 5 Spec No:S421-5.
Review [Ras-cAMP pathway in Saccharomyces cerevisiae]. [Tanpakushitsu Kakusan Koso. 1994]
Review [Ras-cAMP pathway in Saccharomyces cerevisiae].
Toh-e A. Tanpakushitsu Kakusan Koso. 1994 Mar; 39(4):390-401.
The freeze-thaw stress response of the yeast Saccharomyces cerevisiae is growth phase specific and is controlled by nutritional state via the RAS-cyclic AMP signal transduction pathway. [Appl Environ Microbiol. 1997]
The freeze-thaw stress response of the yeast Saccharomyces cerevisiae is growth phase specific and is controlled by nutritional state via the RAS-cyclic AMP signal transduction pathway.
Park JI, Grant CM, Attfield PV, Dawes IW. Appl Environ Microbiol. 1997 Oct; 63(10):3818-24.
Nutrient availability and the RAS/cyclic AMP pathway both induce expression of ribosomal protein genes in Saccharomyces cerevisiae but by different mechanisms. [Mol Cell Biol. 1995]
Nutrient availability and the RAS/cyclic AMP pathway both induce expression of ribosomal protein genes in Saccharomyces cerevisiae but by different mechanisms.
Neuman-Silberberg FS, Bhattacharya S, Broach JR. Mol Cell Biol. 1995 Jun; 15(6):3187-96.

See reviews... See all...

Cited by 50 PubMed Central articles

Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae. [Genetics. 2011]
Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae.
Ramachandran V, Herman PK. Genetics. 2011 Feb; 187(2):441-54. Epub 2010 Nov 15.
Nutrient control of eukaryote cell growth: a systems biology study in yeast. [BMC Biol. 2010]
Nutrient control of eukaryote cell growth: a systems biology study in yeast.
Gutteridge A, Pir P, Castrillo JI, Charles PD, Lilley KS, Oliver SG. BMC Biol. 2010 May 24; 8:68. Epub 2010 May 24.
Mtl1 is required to activate general stress response through Tor1 and Ras2 inhibition under conditions of glucose starvation and oxidative stress. [J Biol Chem. 2010]
Mtl1 is required to activate general stress response through Tor1 and Ras2 inhibition under conditions of glucose starvation and oxidative stress.
Petkova MI, Pujol-Carrion N, Arroyo J, García-Cantalejo J, Angeles de la Torre-Ruiz M. J Biol Chem. 2010 Jun 18; 285(25):19521-31. Epub 2010 Apr 13.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathwa...
RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway.
Trends Genet. 1991 Jan ;7(1):28-33.

PubMed
Demographic history of european populations of Arabidopsis thaliana.
Demographic history of european populations of Arabidopsis thaliana.
PLoS Genet. 2008 May 16 ;4(5):e1000075.

PubMed
A position-effect assay for boundaries of higher order chromosomal domains.
A position-effect assay for boundaries of higher order chromosomal domains.
Cell. 1991 Mar 8 ;64(5):941-50.

PubMed
Mitochondrial gene expression is regulated at multiple levels and differentially...
Mitochondrial gene expression is regulated at multiple levels and differentially in the heart and liver by thyroid hormones.
Curr Genet. 2008 Jul ;54(1):13-22. Epub 2008 May 15 .

PubMed
Structural and genetic properties of the Eb recombinational hotspot in the mouse...
Structural and genetic properties of the Eb recombinational hotspot in the mouse.
Immunogenetics. 1991 ;33(2):132-40.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 50 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information