Ann Genet. 1991;34(3-4):247-51.

Interstitial deletion of chromosome 9q with coexistence of the deleted segment as a ring chromosome. A case report.

Pfeiffer RA, Trautmann U, Hirmer-Stoll R.

Source

Institut für Humangenetik, Friedrich-Alexander Universität Erlangen-Nürnberg, Germany.

Abstract

In a mentally retarded female an interstitial deletion of a chromosome 9 and an additional ring chromosome was shown, which by positive hybridisation with a no 9 library was considered to be the excised segment. The functional centromere and C and DA/DAPI positive material as well on the ring chromosome are explained by a break within the centromere close to the constitutive heterochromatin and supports the hypothesis of "latent" centromere(s).

PMID:: 1809234; [PubMed - indexed for MEDLINE]

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Chromosome 9 Ring - Genetic Alliance

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Cited by 3 PubMed Central articles

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