The synthesis and herbicidal activity of 1-alkyl-3-(alpha-hydroxy-substituted benzylidene)pyrrolidine-2,4-diones

Molecules. 2005 Feb 28;10(2):427-34. doi: 10.3390/10020427.

Abstract

In the search for better herbicides a series of 1-alkyl-3-(alpha-hydroxy-(un)substituted benzylidene)pyrrolidine-2,4-diones were prepared and their structure-activity relationships studied. All their structures have been confirmed by (1)H-NMR and elemental analysis. The preliminary bioassay results indicated that some of them have high herbicidal activity against annual dicotyledonous and monocotyledonous plants.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Hydroxyphenylpyruvate Dioxygenase / antagonists & inhibitors
  • Brassica napus / drug effects
  • Dose-Response Relationship, Drug
  • Echinochloa / drug effects
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / pharmacology
  • Herbicides / chemical synthesis*
  • Herbicides / pharmacology*
  • Models, Biological
  • Structure-Activity Relationship
  • Substrate Specificity
  • Succinimides / chemical synthesis*
  • Succinimides / chemistry
  • Succinimides / pharmacology*

Substances

  • Enzyme Inhibitors
  • Herbicides
  • Succinimides
  • 4-Hydroxyphenylpyruvate Dioxygenase