Genome Res. 2007 Dec;17(12):1783-6. Epub 2007 Nov 7.

A second-generation combined linkage physical map of the human genome.

Matise TC, Chen F, Chen W, De La Vega FM, Hansen M, He C, Hyland FC, Kennedy GC, Kong X, Murray SS, Ziegle JS, Stewart WC, Buyske S.

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Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA. matise@biology.rutgers.edu

Abstract

We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.

PMID:: 17989245; [PubMed - indexed for MEDLINE]
PMCID: PMC2099587

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A second-generation combined linkage physical map of the human genome.

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