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    Int J Drug Policy. 2007 Oct;18(5):352-8. Epub 2007 Aug 7.

    Global estimates of prevalence of HCV infection among injecting drug users.

    Source

    Centre for Research on Drugs and Health Behaviour, London School of Hygiene and Tropical Medicine, University of London, London, UK. carmen.aceijas@lshtm.ac.uk <carmen.aceijas@lshtm.ac.uk>

    Abstract

    OBJECTIVE:

    In this paper, we review evidence of HCV prevalence among injecting drug users (IDUs) worldwide.

    METHODS:

    We undertook a desk-based review of both 'grey' and published literature released between 1998 and 2005.

    RESULTS:

    Data on HCV prevalence among IDUs was found in 57 countries and in 152 sub-national areas. We found reports of HCV prevalence of at least 50% among IDUs in 49 countries or territories. Available regional estimates varied widely, from 10 to 96% in Eastern Europe and Central Asia, from 10 to 100% in South and South-East Asia, from 34 to 93% in East-Asia and the Pacific, from 5 to 60% in North Africa and the Middle-East, from 2 to 100% in Latin America, from 8 to 90% in North America, from 25 to 88% in Australia and New Zealand, and from 2 to 93% in Western Europe. Only in Colombia and Lebanon were all HCV prevalence estimates below 20%. In addition, evidence of HIV/HCV co-infection among IDUs was found in 16 countries. In China, Poland, Puerto Rico, Russia, Spain, Switzerland, Thailand and Viet Nam, estimates of the prevalence of HIV/HCV co-infection among IDUs reached 90%.

    DISCUSSION:

    Taken together, data suggest high global prevalence of HCV and HIV/HCV co-infection among IDUs. We suggest exploring protective factors in sites of low HCV prevalence.

    PMID:
    17854722
    [PubMed - indexed for MEDLINE]

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