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    Platelets. 2007 Sep;18(6):469-71.

    Depression of platelet counts in apparently healthy children with asymptomatic malaria infection in a Nigerian metropolitan city.

    Source

    Postgraduate Haematology Unit, Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria. zacjerry@yahoo.com

    Abstract

    Asymptomatic malaria infection is a common feature of malaria endemic regions in the tropics. In this prospective cross sectional survey, involving 240 children aged 1 to 8 years (Boys = 117, Girls = 123; Ratio 1:1.05), the median platelet count was 115 x 10(9)/L (IQR 97.5-190). Thirty-three out of 240 (13.75%) of the children had thrombocytopenia (platelet count < 100 x 10(9)/L). Malaria parasite was found to exert significant reduction in platelet count. This reduction was more pronounced in children under 5 years and also at higher parasite counts. An inverse relationship was established between parasite density and platelet count (y = -0.017x + 96.2, r = -0.2). Thrombocytopenia is not only a feature of acute malaria infection but also that of asymptomatic malaria infection in the tropics and might be a useful indicator of malaria in children.

    PMID:
    17763156
    [PubMed - indexed for MEDLINE]

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