Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11037-41.

Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in humans.

Ribary U, Ioannides AA, Singh KD, Hasson R, Bolton JP, Lado F, Mogilner A, Llinás R.

Source

Department of Physiology and Biophysics, New York University Medical Center, NY 10016.

Abstract

This paper introduces the use of magnetic field tomography (MFT), a noninvasive technique based on distributed source analysis of magnetoencephalography data, which makes possible the three-dimensional reconstruction of dynamic brain activity in humans. MFT has a temporal resolution better than 1 msec and a spatial accuracy of 2-5 mm at the cortical level, which deteriorates to 1-3 cm at depths of 6 cm or more. MFT is used here to visualize the origin of a spatiotemporally organized pattern of coherent 40-Hz electrical activity. This coherence, initially observed during auditory input, was proposed to be generated by recurrent corticothalamic oscillation. In support of this hypothesis, we illustrate well-defined 40-Hz coherence between cortical-subcortical sites with a time shift that is consistent with thalamocortical conduction times. Studies on Alzheimer patients indicate that, while a similar activity pattern is present, the cortical component is reduced in these subjects.

PMID:: 1763020; [PubMed - indexed for MEDLINE]
PMCID:: PMC53068

Free PMC Article

Publication Types, MeSH Terms

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

MRI Scans - MedlinePlus Health Information

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Cortically-induced coherence of a thalamic-generated oscillation. [Neuroscience. 1999]
Cortically-induced coherence of a thalamic-generated oscillation.
Destexhe A, Contreras D, Steriade M. Neuroscience. 1999; 92(2):427-43.
Spatiotemporal patterns of spindle oscillations in cortex and thalamus. [J Neurosci. 1997]
Spatiotemporal patterns of spindle oscillations in cortex and thalamus.
Contreras D, Destexhe A, Sejnowski TJ, Steriade M. J Neurosci. 1997 Feb 1; 17(3):1179-96.
Corticothalamic inputs control the pattern of activity generated in thalamocortical networks. [J Neurosci. 2000]
Corticothalamic inputs control the pattern of activity generated in thalamocortical networks.
Blumenfeld H, McCormick DA. J Neurosci. 2000 Jul 1; 20(13):5153-62.
Review Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance. [Cereb Cortex. 1997]
Review Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance.
Steriade M. Cereb Cortex. 1997 Sep; 7(6):583-604.
Review Cortical and subcortical generators of normal and abnormal rhythmicity. [Int Rev Neurobiol. 2002]
Review Cortical and subcortical generators of normal and abnormal rhythmicity.
McCormick DA. Int Rev Neurobiol. 2002; 49:99-114.

See reviews... See all...

Cited by 44 PubMed Central articles

The auditory and non-auditory brain areas involved in tinnitus. An emergent property of multiple parallel overlapping subnetworks. [Front Syst Neurosci. 2012]
The auditory and non-auditory brain areas involved in tinnitus. An emergent property of multiple parallel overlapping subnetworks.
Vanneste S, De Ridder D. Front Syst Neurosci. 2012; 6:31. Epub 2012 May 8.
Gamma band activity in the reticular activating system. [Front Neurol. 2012]
Gamma band activity in the reticular activating system.
Urbano FJ, Kezunovic N, Hyde J, Simon C, Beck P, Garcia-Rill E. Front Neurol. 2012; 3:6. Epub 2012 Jan 31.
Lateral information processing by spiking neurons: a theoretical model of the neural correlate of consciousness. [Comput Intell Neurosci. 2011]
Lateral information processing by spiking neurons: a theoretical model of the neural correlate of consciousness.
Ebner M, Hameroff S. Comput Intell Neurosci. 2011; 2011:247879. Epub 2011 Oct 23.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in huma...
Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in humans.
Proc Natl Acad Sci U S A. 1991 Dec 15 ;88(24):11037-41.

PubMed
Uterine cervical teratoma with divergent neuroepithelial differentiation and dev...
Uterine cervical teratoma with divergent neuroepithelial differentiation and development of an oligodendroglioma: report of a case and review of the literature.
Ann Diagn Pathol. 2007 Aug ;11(4):293-6.

PubMed
RNA editing makes mistakes in plant mitochondria: editing loses sense in transcr...
RNA editing makes mistakes in plant mitochondria: editing loses sense in transcripts of a rps19 pseudogene and in creating stop codons in coxI and rps3 mRNAs of Oenothera.
Nucleic Acids Res. 1991 Dec 25 ;19(24):6923-8.

PubMed
Valuing reductions in on-the-job illness: 'presenteeism' from managerial and eco...
Valuing reductions in on-the-job illness: 'presenteeism' from managerial and economic perspectives.
Health Econ. 2008 Apr ;17(4):469-85.

PubMed
Identification of a new non-neuronal cell type in rat olfactory epithelium.
Identification of a new non-neuronal cell type in rat olfactory epithelium.
Neuroscience. 1991 ;45(2):433-49.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: