Clin Exp Obstet Gynecol. 1991;18(3):161-4.

Distribution of immunoreactive relaxin in the genital tract and in the mammary gland of non-pregnant women.

Bongers-Binder S, Burgardt A, Seeger H, Voelter W, Lippert TH.

Source

Department of Obstetrics and Gynecology, University of Tübingen, FRG.

Abstract

Relaxin was determined in healthy and pathological tissue samples from mammary gland, ovary, myometrium and cervix uteri of non-pregnant women. Relaxin could be detected in all groups of tissues examined. The highest values were found in healthy ovary, the lowest concentrations in the cervix, which is known as a target organ for relaxin activity during pregnancy. Mammary parenchyma showed the highest specific activity of all healthy tissues examined. The relaxin concentration in myoma tissue is significantly higher than in healthy myometrium.

PMID:: 1752047; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

Relaxin

LinkOut - more resources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Comparison of cytosolic p53 protein levels in the female genital tract and breast, and their tumors. [Tumour Biol. 2000]
Comparison of cytosolic p53 protein levels in the female genital tract and breast, and their tumors.
Westhof G, Bader W, Greiner-Mai E, Hatzmann W. Tumour Biol. 2000 May-Jun; 21(3):123-34.
Immunohistochemical demonstration of relaxin in the genital tract of pregnant and nonpregnant women. [J Clin Endocrinol Metab. 1983]
Immunohistochemical demonstration of relaxin in the genital tract of pregnant and nonpregnant women.
Yki-Järvinen H, Wahlström T, Seppälä M. J Clin Endocrinol Metab. 1983 Sep; 57(3):451-4.
Immunohistochemical localization of specific relaxin-binding cells in the cervix, mammary glands, and nipples of pregnant rats. [Endocrinology. 1995]
Immunohistochemical localization of specific relaxin-binding cells in the cervix, mammary glands, and nipples of pregnant rats.
Kuenzi MJ, Sherwood OD. Endocrinology. 1995 Apr; 136(4):1367-73.
Review Relaxin--a review. [Aust N Z J Obstet Gynaecol. 1981]
Review Relaxin--a review.
MacLennan AH. Aust N Z J Obstet Gynaecol. 1981 Nov; 21(4):195-202.
Review [Estrogen receptors in the genital tract of the climacteric woman]. [Rev Med Univ Navarra. 1991]
Review [Estrogen receptors in the genital tract of the climacteric woman].
Pérez-López FR, Campo López C. Rev Med Univ Navarra. 1991 Oct-Dec; 36(4):17-31.

See reviews... See all...

Cited by 2 PubMed Central articles

Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells. [Breast Cancer Res. 2008]
Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells.
Radestock Y, Hoang-Vu C, Hombach-Klonisch S. Breast Cancer Res. 2008; 10(4):R71. Epub 2008 Aug 21.
Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates. [Reprod Biol Endocrinol. 2003]
Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates.
Ivell R, Balvers M, Pohnke Y, Telgmann R, Bartsch O, Milde-Langosch K, Bamberger AM, Einspanier A. Reprod Biol Endocrinol. 2003 Nov 24; 1:114. Epub 2003 Nov 24.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Distribution of immunoreactive relaxin in the genital tract and in the mammary g...
Distribution of immunoreactive relaxin in the genital tract and in the mammary gland of non-pregnant women.
Clin Exp Obstet Gynecol. 1991 ;18(3):161-4.

PubMed
Resistance exercise reverses aging in human skeletal muscle.
Resistance exercise reverses aging in human skeletal muscle.
PLoS One. 2007 May 23 ;2(5):e465.

PubMed
Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea mod...
Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo.
J Cancer Res Clin Oncol. 1991 ;117(6):526-32.

PubMed
Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with pl...
Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, and prostate cancer risk.
Prostate. 2007 Jun 15 ;67(9):911-23.

PubMed
Modelling the influence of risk factors on familial aggregation of disease.
Modelling the influence of risk factors on familial aggregation of disease.
Biometrics. 1991 Sep ;47(3):933-45.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: