Am J Obstet Gynecol. 1992 Jan;166(1 Pt 1):167-8.

Rapid growth of leiomyoma in patient receiving tamoxifen.

Dilts PV Jr, Hopkins MP, Chang AE, Cody RL.

Source

Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor 48109-0718.

Abstract

A 49-year-old patient with breast cancer had a leiomyoma that rapidly enlarged shortly after she started therapy with tamoxifen. Exploratory laparotomy was necessary to confirm the diagnosis. The rapid growth may have resulted from the estrogen agonist properties of tamoxifen or alternatively by ovarian stimulation resulting in endogenous estrogen production.

PMID:: 1733191; [PubMed - indexed for MEDLINE]

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Cited by 5 PubMed Central articles

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