Semin Fetal Neonatal Med. 2007 Aug;12(4):250-8. Epub 2007 Feb 23.

Epo and other hematopoietic factors.

Source

Department of Pediatrics, Division of Neonatology, Health Sciences Building, University of Washington, Box 356320, Seattle, WA 98195, USA. sjuul@u.washington.edu

Abstract

The growth factors erythropoietin and granulocyte-colony stimulating factor have hematopoietic and non-hematopoietic functions. Both are used clinically in their recombinant forms. Both also have interesting tissue-protective effects in other organs, which are unrelated to their hematopoietic functions. They have clinical hematopoietic uses in neonatal populations and in experimental non-hematopoietic research, and clinical potential as neuroprotective or tissue-protective agents.

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PMCID: PMC2018740

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