J Rehabil Res Dev. 2006 Sep-Oct;43(6):713-22.

Migration and proliferation of retinal pigment epithelium on extracellular matrix ligands.

Wang H, Van Patten Y, Sugino IK, Zarbin MA.

Source

Institute of Opthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA.

Abstract

We compared aged adult and fetal retinal pigment epithelium (RPE) migration and proliferation in cell culture. Aged adult RPE resurfaced on dishes coated with human or mouse laminin, human or rat collagen I, human or mouse collagen IV, or human fibronectin. Resurfacing was best on bovine corneal endothelial cell extracellular matrix. Resurfacing was worst on mouse laminin. Fetal RPE resurfacing was robust on all surfaces studied except human and mouse laminin. In general, fetal RPE resurfacing was much greater than that seen with aged RPE on comparable surfaces. The degree of cell proliferation (labeled by Ki-67) was much greater in fetal than adult RPE cells.

PMID:: 17310420; [PubMed - indexed for MEDLINE]

Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Libraries

LinkOut Holdings

Supplemental Content

Icon for Department of Veterans Affairs, Rehabilitation Research & Development Service

Save items

Related citations in PubMed

Extracellular matrix ligands promote RPE attachment to inner Bruch's membrane. [Curr Eye Res. 2002]
Extracellular matrix ligands promote RPE attachment to inner Bruch's membrane.
Del Priore LV, Geng L, Tezel TH, Kaplan HJ. Curr Eye Res. 2002 Aug; 25(2):79-89.
Culture-induced increase in alpha integrin subunit expression in retinal pigment epithelium is important for improved resurfacing of aged human Bruch's membrane. [Exp Eye Res. 2008]
Culture-induced increase in alpha integrin subunit expression in retinal pigment epithelium is important for improved resurfacing of aged human Bruch's membrane.
Gullapalli VK, Sugino IK, Zarbin MA. Exp Eye Res. 2008 Feb; 86(2):189-200. Epub 2007 Dec 11.
Corneal endothelial cell matrix promotes expression of differentiated features of retinal pigmented epithelial cells: implication of laminin and basic fibroblast growth factor as active components. [Exp Eye Res. 1993]
Corneal endothelial cell matrix promotes expression of differentiated features of retinal pigmented epithelial cells: implication of laminin and basic fibroblast growth factor as active components.
Campochiaro PA, Hackett SF. Exp Eye Res. 1993 Nov; 57(5):539-47.
Review RPE cell cultivation. [Graefes Arch Clin Exp Ophthalm...]
Review RPE cell cultivation.
Engelmann K, Valtink M. Graefes Arch Clin Exp Ophthalmol. 2004 Jan; 242(1):65-7. Epub 2003 Dec 5.
Review [Molecular mechanisms of organogenesis regulated by ECM: the role in epithelial branching morphogenesis]. [Tanpakushitsu Kakusan Koso. 2006]
Review [Molecular mechanisms of organogenesis regulated by ECM: the role in epithelial branching morphogenesis].
Sakai T. Tanpakushitsu Kakusan Koso. 2006 May; 51(6 Suppl):600-5.

See reviews... See all...

Cited by 3 PubMed Central articles

Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane. [Invest Ophthalmol Vis Sci. 2011]
Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane.
Sugino IK, Gullapalli VK, Sun Q, Wang J, Nunes CF, Cheewatrakoolpong N, Johnson AC, Degner BC, Hua J, Liu T, et al. Invest Ophthalmol Vis Sci. 2011 Mar; 52(3):1345-58. Epub 2011 Mar 10.
Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro. [Invest Ophthalmol Vis Sci. 2010]
Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro.
He S, Kumar SR, Zhou P, Krasnoperov V, Ryan SJ, Gill PS, Hinton DR. Invest Ophthalmol Vis Sci. 2010 Jan; 51(1):543-52. Epub 2009 Aug 20.
Isolation and characterization of a spontaneously immortalized bovine retinal pigmented epithelial cell line. [BMC Cell Biol. 2009]
Isolation and characterization of a spontaneously immortalized bovine retinal pigmented epithelial cell line.
Liggett TE, Griffiths TD, Gaillard ER. BMC Cell Biol. 2009 May 4; 10:33. Epub 2009 May 4.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Migration and proliferation of retinal pigment epithelium on extracellular matri...
Migration and proliferation of retinal pigment epithelium on extracellular matrix ligands.
J Rehabil Res Dev. 2006 Sep-Oct ;43(6):713-22.

PubMed
T cell-mediated lethal shock triggered in mice by the superantigen staphylococca...
T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor.
J Exp Med. 1992 Jan 1 ;175(1):91-8.

PubMed
Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptio...
Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2.
J Clin Immunol. 2007 Mar ;27(2):210-20. Epub 2007 Feb 17 .

PubMed
Localization of the nucleolar protein NO38 in amphibian oocytes.
Localization of the nucleolar protein NO38 in amphibian oocytes.
J Cell Biol. 1992 Jan ;116(1):1-14.

PubMed
Ikaros and chromatin regulation in early hematopoiesis.
Ikaros and chromatin regulation in early hematopoiesis.
Curr Opin Immunol. 2007 Apr ;19(2):116-22. Epub 2007 Feb 20 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Migration and proliferation of retinal pigment epithelium on extracellular matrix ligands.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information