Hippocampus. 2007;17(1):1-4.

Polyribosomes are increased in spines of CA1 dendrites 2 h after the induction of LTP in mature rat hippocampal slices.

Bourne JN, Sorra KE, Hurlburt J, Harris KM.

Source

Synapses and Cognitive Neuroscience Center, Medical College of Georgia, Augusta, Georgia, USA.

Abstract

Enduring long-term potentiation (LTP) requires immediate protein synthesis, hence we assessed whether more polyribosomes are present in dendritic spines of mature hippocampal dendrites after the induction of LTP. Reconstructions from serial section transmission electron microscopy (sSTEM) revealed more dendritic polyribosomes 2 h posttetanus, relative to low-frequency stimulation (LFS). Polyribosomes were present in spines of all shapes with larger postsynaptic densities after 2 h, suggesting a coordinated local protein synthesis among many synapses to replenish proteins utilized during an earlier phase of LTP.

PMID:: 17094086; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Coordination of size and number of excitatory and inhibitory synapses results in a balanced structural plasticity along mature hippocampal CA1 dendrites during LTP. [Hippocampus. 2011]
Coordination of size and number of excitatory and inhibitory synapses results in a balanced structural plasticity along mature hippocampal CA1 dendrites during LTP.
Bourne JN, Harris KM. Hippocampus. 2011 Apr; 21(4):354-73.
Polyribosomes redistribute from dendritic shafts into spines with enlarged synapses during LTP in developing rat hippocampal slices. [Neuron. 2002]
Polyribosomes redistribute from dendritic shafts into spines with enlarged synapses during LTP in developing rat hippocampal slices.
Ostroff LE, Fiala JC, Allwardt B, Harris KM. Neuron. 2002 Aug 1; 35(3):535-45.
Chemically induced long-term potentiation increases the number of perforated and complex postsynaptic densities but does not alter dendritic spine volume in CA1 of adult mouse hippocampal slices. [Eur J Neurosci. 2005]
Chemically induced long-term potentiation increases the number of perforated and complex postsynaptic densities but does not alter dendritic spine volume in CA1 of adult mouse hippocampal slices.
Stewart MG, Medvedev NI, Popov VI, Schoepfer R, Davies HA, Murphy K, Dallérac GM, Kraev IV, Rodríguez JJ. Eur J Neurosci. 2005 Jun; 21(12):3368-78.
Review The role of endosomal-recycling in long-term potentiation. [Cell Mol Life Sci. 2011]
Review The role of endosomal-recycling in long-term potentiation.
Kelly EE, Horgan CP, McCaffrey MW, Young P. Cell Mol Life Sci. 2011 Jan; 68(2):185-94. Epub 2010 Sep 6.
Review Local protein synthesis, actin dynamics, and LTP consolidation. [Curr Opin Neurobiol. 2008]
Review Local protein synthesis, actin dynamics, and LTP consolidation.
Bramham CR. Curr Opin Neurobiol. 2008 Oct; 18(5):524-31. Epub 2008 Oct 14.

See reviews... See all...

Cited by 8 PubMed Central articles

Single-molecule imaging of translational output from individual RNA granules in neurons. [Mol Biol Cell. 2012]
Single-molecule imaging of translational output from individual RNA granules in neurons.
Tatavarty V, Ifrim MF, Levin M, Korza G, Barbarese E, Yu J, Carson JH. Mol Biol Cell. 2012 Mar; 23(5):918-29. Epub 2012 Jan 4.
Fear and safety learning differentially affect synapse size and dendritic translation in the lateral amygdala. [Proc Natl Acad Sci U S A. 2010]
Fear and safety learning differentially affect synapse size and dendritic translation in the lateral amygdala.
Ostroff LE, Cain CK, Bedont J, Monfils MH, Ledoux JE. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9418-23. Epub 2010 May 3.
Pin1 and PKMzeta sequentially control dendritic protein synthesis. [Sci Signal. 2010]
Pin1 and PKMzeta sequentially control dendritic protein synthesis.
Westmark PR, Westmark CJ, Wang S, Levenson J, O'Riordan KJ, Burger C, Malter JS. Sci Signal. 2010 Mar 9; 3(112):ra18. Epub 2010 Mar 9.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Polyribosomes are increased in spines of CA1 dendrites 2 h after the induction o...
Polyribosomes are increased in spines of CA1 dendrites 2 h after the induction of LTP in mature rat hippocampal slices.
Hippocampus. 2007 ;17(1):1-4.

PubMed
Generation of a functional cDNA encoding the LdH2 class-I molecule by using a si...
Generation of a functional cDNA encoding the LdH2 class-I molecule by using a single-LTR retroviral shuttle vector.
Gene. 1991 Jan 15 ;97(2):213-21.

PubMed
Analysis of ancient sequence motifs in the H-PPase family.
Analysis of ancient sequence motifs in the H-PPase family.
FEBS J. 2006 Nov ;273(22):5183-93. Epub 2006 Oct 20 .

PubMed
micF RNA in ompB mutants of Escherichia coli: different pathways regulate micF R...
micF RNA in ompB mutants of Escherichia coli: different pathways regulate micF RNA levels in response to osmolarity and temperature change.
J Bacteriol. 1990 Aug ;172(8):4143-50.

PubMed
Refuting phylogenetic relationships.
Refuting phylogenetic relationships.
Biol Direct. 2006 Sep 6 ;1:26.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Polyribosomes are increased in spines of CA1 dendrites 2 h after the induction of LTP in mature rat hippocampal slices.

Source

Abstract

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 8 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information