Warning: The NCBI web site requires JavaScript to function. more...

My NCBI Sign In

J Virol. 2007 Jan;81(2):1033-6. Epub 2006 Nov 1.

Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma.

Kim do N, Chae HS, Oh ST, Kang JH, Park CH, Park WS, Takada K, Lee JM, Lee WK, Lee SK.

Source

Research Institute of Immunobiology, Catholic University of Korea, Seoul, Korea.

Abstract

Epstein-Barr virus (EBV) is associated with about 6 to 16% of gastric carcinoma cases worldwide. Expression of the EBV microRNAs (miRNAs) was observed in B cells and nasopharyngeal carcinoma cells infected with EBV. However, it is not clear if the EBV miRNAs are expressed in EBV-associated gastric carcinomas (EBVaGCs). We found that BART miRNAs but not BHRF1 miRNAs were expressed in EBV-infected gastric carcinoma cell lines and the tumor tissues from patients as well as the animal model. The expression of viral miRNAs in EBVaGCs suggests that these EBV miRNAs may play important roles in the tumorigenesis of EBVaGCs.

PMID:: 17079300; [PubMed - indexed for MEDLINE]
PMCID: PMC1797424

Free PMC Article

Images from this publication.See all images (3) Free text

FIG. 2.

FIG. 3.

FIG. 1.

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Stomach Cancer - MedlinePlus Health Information

Libraries

LinkOut Holdings

Supplemental Content

Click here to read

Click here to read

Related citations

[Expression of Epstein-Barr virus genes in EBV-associated gastric carcinoma]. [Ai Zheng. 2004]
[Expression of Epstein-Barr virus genes in EBV-associated gastric carcinoma].
Wang Y, Luo B, Zhao P, Huang BH. Ai Zheng. 2004 Jul; 23(7):782-7.
Correlation of Epstein-Barr virus and its encoded proteins with Helicobacter pylori and expression of c-met and c-myc in gastric carcinoma. [World J Gastroenterol. 2006]
Correlation of Epstein-Barr virus and its encoded proteins with Helicobacter pylori and expression of c-met and c-myc in gastric carcinoma.
Luo B, Wang Y, Wang XF, Gao Y, Huang BH, Zhao P. World J Gastroenterol. 2006 Mar 28; 12(12):1842-8.
Expression of Epstein-Barr virus genes in EBV-associated gastric carcinomas. [World J Gastroenterol. 2005]
Expression of Epstein-Barr virus genes in EBV-associated gastric carcinomas.
Luo B, Wang Y, Wang XF, Liang H, Yan LP, Huang BH, Zhao P. World J Gastroenterol. 2005 Feb 7; 11(5):629-33.
Review Epstein-Barr virus and gastric carcinoma. [Mol Pathol. 2000]
Review Epstein-Barr virus and gastric carcinoma.
Takada K. Mol Pathol. 2000 Oct; 53(5):255-61.
Review Epstein-Barr virus (EBV) infection and gastric carcinoma: the approach through EBV infected epithelial cell lines. [Jpn J Infect Dis. 1999]
Review Epstein-Barr virus (EBV) infection and gastric carcinoma: the approach through EBV infected epithelial cell lines.
Sairenji T. Jpn J Infect Dis. 1999 Jun; 52(3):110-2.

See reviews... See all...

Cited by 21 PubMed Central articles

Expression of BamHI-A Rightward Transcripts in Epstein-Barr Virus-Associated Gastric Cancers. [Cancer Res Treat. 2011]
Expression of BamHI-A Rightward Transcripts in Epstein-Barr Virus-Associated Gastric Cancers.
Jang BG, Jung EJ, Kim WH. Cancer Res Treat. 2011 Dec; 43(4):250-4. Epub 2011 Dec 27.
Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas. [PLoS One. 2011]
Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas.
Ramakrishnan R, Donahue H, Garcia D, Tan J, Shimizu N, Rice AP, Ling PD. PLoS One. 2011; 6(11):e27271. Epub 2011 Nov 10.
A novel persistence associated EBV miRNA expression profile is disrupted in neoplasia. [PLoS Pathog. 2011]
A novel persistence associated EBV miRNA expression profile is disrupted in neoplasia.
Qiu J, Cosmopoulos K, Pegtel M, Hopmans E, Murray P, Middeldorp J, Shapiro M, Thorley-Lawson DA. PLoS Pathog. 2011 Aug; 7(8):e1002193. Epub 2011 Aug 25.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma...
Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma.
J Virol. 2007 Jan ;81(2):1033-6. Epub 2006 Nov 1 .

PubMed
Retrovirus restriction factors.
Retrovirus restriction factors.
Mol Cell. 2004 Dec 22 ;16(6):849-59.

PubMed
Nuclear Factor 90, a cellular dsRNA binding protein inhibits the HIV Rev-export ...
Nuclear Factor 90, a cellular dsRNA binding protein inhibits the HIV Rev-export function.
Retrovirology. 2006 Nov 24 ;3:83.

PubMed
HIV-1: molecular biology and pathogenesis.
HIV-1: molecular biology and pathogenesis.
Adv Pharmacol. 2000 ;48:xvii-xix.

PubMed
MicroRNA maturation: stepwise processing and subcellular localization.
MicroRNA maturation: stepwise processing and subcellular localization.
EMBO J. 2002 Sep 2 ;21(17):4663-70.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Literature > PubMed

Write to the Help Desk