Oncogene. 2006 Oct 9;25(46):6163-9.

Principles and effects of microRNA-mediated post-transcriptional gene regulation.

Source

Division of Gene regulation and Expression, College of Life Sciences, University of Dundee, Dundee, UK.

Abstract

MicroRNAs (miRNAs) are abundant regulatory RNAs involved in the regulation of many key biological processes. Recent advances in understanding the mechanism of RNA interference and miRNA-mediated mechanisms shed light on major principals of the formation of the regulatory complex and provide models to explain how these small regulatory RNA species interfere with gene expression and how they influence the translational status of the transcriptome.

PMID:: 17028595; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

MicroRNAs

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Libraries

LinkOut Holdings

Supplemental Content

Related citations

Review Post-transcriptional gene silencing by siRNAs and miRNAs. [Curr Opin Struct Biol. 2005]
Review Post-transcriptional gene silencing by siRNAs and miRNAs.
Filipowicz W, Jaskiewicz L, Kolb FA, Pillai RS. Curr Opin Struct Biol. 2005 Jun; 15(3):331-41.
Review Gene silencing in vitro and in vivo using intronic microRNAs. [Methods Mol Biol. 2006]
Review Gene silencing in vitro and in vivo using intronic microRNAs.
Lin SL, Ying SY. Methods Mol Biol. 2006; 342:295-312.
miRNAs regulate miRNAs: coordinated transcriptional and post-transcriptional regulation. [Cell Cycle. 2006]
miRNAs regulate miRNAs: coordinated transcriptional and post-transcriptional regulation.
Tuccoli A, Poliseno L, Rainaldi G. Cell Cycle. 2006 Nov 1; 5(21):2473-6. Epub 2006 Sep 19.
Review MicroRNAs and their regulatory roles in animals and plants. [J Cell Physiol. 2007]
Review MicroRNAs and their regulatory roles in animals and plants.
Zhang B, Wang Q, Pan X. J Cell Physiol. 2007 Feb; 210(2):279-89.
Review Intron-mediated RNA interference and microRNA (miRNA). [Front Biosci. 2008]
Review Intron-mediated RNA interference and microRNA (miRNA).
Lin SL, Kim H, Ying SY. Front Biosci. 2008 Jan 1; 13:2216-30. Epub 2008 Jan 1.

See reviews... See all...

Cited by 34 PubMed Central articles

Selection and validation of reference genes for miRNA expression studies during porcine pregnancy. [PLoS One. 2011]
Selection and validation of reference genes for miRNA expression studies during porcine pregnancy.
Wessels JM, Edwards AK, Zettler C, Tayade C. PLoS One. 2011; 6(12):e28940. Epub 2011 Dec 12.
miR-143 regulation of prostaglandin-endoperoxidase synthase 2 in the amnion: implications for human parturition at term. [PLoS One. 2011]
miR-143 regulation of prostaglandin-endoperoxidase synthase 2 in the amnion: implications for human parturition at term.
Kim SY, Romero R, Tarca AL, Bhatti G, Lee J, Chaiworapongsa T, Hassan SS, Kim CJ. PLoS One. 2011; 6(9):e24131. Epub 2011 Sep 7.
Targeted delivery of mutant tolerant anti-coxsackievirus artificial microRNAs using folate conjugated bacteriophage Phi29 pRNA. [PLoS One. 2011]
Targeted delivery of mutant tolerant anti-coxsackievirus artificial microRNAs using folate conjugated bacteriophage Phi29 pRNA.
Ye X, Liu Z, Hemida MG, Yang D. PLoS One. 2011; 6(6):e21215. Epub 2011 Jun 15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Principles and effects of microRNA-mediated post-transcriptional gene regulation...
Principles and effects of microRNA-mediated post-transcriptional gene regulation.
Oncogene. 2006 Oct 9 ;25(46):6163-9.

PubMed
An open letter to Colonel Muammar al-Gaddafi.
An open letter to Colonel Muammar al-Gaddafi.
Nature. 2006 Nov 9 ;444(7116):146.

PubMed
Emergence of resistant human immunodeficiency virus type 1 in patients receiving...
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.
Antimicrob Agents Chemother. 2002 Jun ;46(6):1896-905.

PubMed
The young and the restless.
The young and the restless.
Nat Med. 2007 Jun ;13(6):649.

PubMed
Endogenous retroviruses: Thierry Heidmann wins the 2009 Retrovirology prize.
Endogenous retroviruses: Thierry Heidmann wins the 2009 Retrovirology prize.
Retrovirology. 2009 Dec 1 ;6:108.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: