Nature. 1990 Nov 15;348(6298):213-6.

Isolation of an endogenously processed immunodominant viral peptide from the class I H-2Kb molecule.

Source

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461.

Abstract

Using an approach for isolating and characterizing peptide fractions that are intracellularly associated with major histocompatibility complex class I molecules, the major peptide recognized by cytotoxic T cells specific for the vesicular stomatitis virus has been isolated from the H-2Kb molecule of infected cells. This endogenously processed octapeptide is allele-specific as it does not bind to H-2Db molecules, and contains the core sequence of the epitope of the nucleocapsid protein of the vesicular stomatitis virus identified by testing with exogenous synthetic peptides.

Comment in

Nature. 1990 Nov 15;348(6298):195-7.

PMID:: 1700303; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. [Proc Natl Acad Sci U S A. 1992]
Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.
Zhang W, Young AC, Imarai M, Nathenson SG, Sacchettini JC. Proc Natl Acad Sci U S A. 1992 Sep 1; 89(17):8403-7.
Possible mechanisms by which the H-2Kbm3 mutation may decrease cytotoxic T-lymphocyte recognition of vesicular stomatitis virus nucleoprotein antigen. [J Virol. 1987]
Possible mechanisms by which the H-2Kbm3 mutation may decrease cytotoxic T-lymphocyte recognition of vesicular stomatitis virus nucleoprotein antigen.
Bowman MR, Lyles DS, Parce JW. J Virol. 1987 Jun; 61(6):1992-8.
Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus. [Proc Natl Acad Sci U S A. 1992]
Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus.
Shibata K, Imarai M, van Bleek GM, Joyce S, Nathenson SG. Proc Natl Acad Sci U S A. 1992 Apr 1; 89(7):3135-9.
Review T cell recognition of hepatitis B and C viral antigens. [Eur J Clin Invest. 1994]
Review T cell recognition of hepatitis B and C viral antigens.
Jung MC, Diepolder HM, Pape GR. Eur J Clin Invest. 1994 Oct; 24(10):641-50.
Review Mouse histocompatibility antigens. [Angew Chem Int Ed Engl. 1978]
Review Mouse histocompatibility antigens.
Henning R. Angew Chem Int Ed Engl. 1978 May; 17(5):342-50.

See reviews... See all...

Cited by over 100 PubMed Central articles

Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection. [PLoS Pathog. 2011]
Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection.
Moltedo B, Li W, Yount JS, Moran TM. PLoS Pathog. 2011 Nov; 7(11):e1002345. Epub 2011 Nov 3.
Review Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes. [Immunol Res. 2011]
Review Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.
Anikeeva N, Sykulev Y. Immunol Res. 2011 Dec; 51(2-3):183-94.
Recognition of class I MHC by a rat Ly49 NK cell receptor is dependent on the identity of the P2 anchor amino acid of bound peptide. [J Immunol. 2011]
Recognition of class I MHC by a rat Ly49 NK cell receptor is dependent on the identity of the P2 anchor amino acid of bound peptide.
Ma BJ, Kane KP. J Immunol. 2011 Sep 15; 187(6):3267-76. Epub 2011 Aug 12.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Isolation of an endogenously processed immunodominant viral peptide from the cla...
Isolation of an endogenously processed immunodominant viral peptide from the class I H-2Kb molecule.
Nature. 1990 Nov 15 ;348(6298):213-6.

PubMed
Impact of a harm-reduction policy on HIV and hepatitis C virus transmission amon...
Impact of a harm-reduction policy on HIV and hepatitis C virus transmission among drug users: recent French data--the ANRS-Coquelicot Study.
Subst Use Misuse. 2006 ;41(10-12):1603-21.

PubMed
Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional se...
Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences.
J Exp Med. 1990 Nov 1 ;172(5):1377-90.

PubMed
Systematic reviews of qualitative evidence: what are the experiences of women wi...
Systematic reviews of qualitative evidence: what are the experiences of women with endometriosis?
J Obstet Gynaecol. 2006 Aug ;26(6):501-6.

PubMed
Comparison of cisplatin and carboplatin cytotoxicity in human ovarian cancer cel...
Comparison of cisplatin and carboplatin cytotoxicity in human ovarian cancer cell lines using the MTT assay.
Gynecol Oncol. 1990 Nov ;39(2):119-22.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Isolation of an endogenously processed immunodominant viral peptide from the class I H-2Kb molecule.

Source

Abstract

Comment in

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by over 100 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information