Crit Care. 2006;10(5):164.

Antimicrobial resistance and patient outcomes: the hazards of adjustment.

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Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. mitchells@tasmc.health.gov.il

Abstract

Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables--events in the causal pathway between the exposure and the outcome--when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue.

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PMCID: PMC1751076

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Antimicrobial resistance and patient outcomes: the hazards of adjustment.

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