J Gen Microbiol. 1990 Apr;136(4):713-6.

A breakdown in macromolecular synthesis preceding differentiation in Streptomyces coelicolor A3(2).

Granozzi C, Billetta R, Passantino R, Sollazzo M, Puglia AM.

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Dipartimento di Biologia Cellulare e dello Sviluppo, Sezione di Genetica, Università di Palermo, Italy.

Abstract

A transitory cessation of growth was recorded in Streptomyces coelicolor A3(2) at the end of vegetative mycelium formation on solid medium. In the same phase a striking reduction in protein and nucleic acid synthesis was detected. Growth and macromolecular synthesis resumed, nearly reaching the original values, when morphological differentiation occurred. It is concluded that a physiological stress occurs within the bacterial population just before the onset of the morphological differentiation.

PMID:: 1697885; [PubMed - indexed for MEDLINE]

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