J Exp Med. 1990 Jul 1;172(1):379-82.

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

Blackman MJ, Heidrich HG, Donachie S, McBride JS, Holder AA.

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Division of Parasitology, National Institute for Medical Research, London, United Kingdom.

Abstract

A complex of polypeptides derived from a precursor is present on the surface of the malaria merozoite. During erythrocyte invasion only a small fragment from this complex is retained on the parasite surface and carried into the newly infected red cell. Antibodies to this fragment will interrupt invasion.

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A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

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