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    J Clin Microbiol. 2006 Aug;44(8):2967-9.

    Impact of laboratory cross-contamination on molecular epidemiology studies of tuberculosis.

    Source

    Complejo Hospitalario Torrecárdenas, Almería, Spain.

    Abstract

    Laboratory cross-contamination by Mycobacterium tuberculosis is known to be responsible for the misdiagnosis of tuberculosis, but its impact on other contexts has not been analyzed. We present the findings of a molecular epidemiology analysis in which the recent transmission events identified by a genotyping reference center were overestimated as a result of unnoticed laboratory cross-contamination in the original diagnostic laboratories.

    PMID:
    16891518
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC1594630
    Free PMC Article

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