Arthritis Res Ther. 2006;8(3):209. Epub 2006 May 11.

Anti-inflammatory and immunosuppressive drugs and reproduction.

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Department of Rheumatology and Clinical Immunology/Allergology, University Hospital of Bern, Switzerland. monika.oestensen@insel.ch

Abstract

Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.

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PMCID: PMC1526635

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