Hereditas. 1991;115(1):69-72.

Refinement of localization of the human genes for myeloperoxidase (MPO), protein kinase C, alpha polypeptide, PRKCA, and the DNA fragment D17S21 on chromosome 17q.

Latos-Bielenska A, Klett C, Just W, Hameister H.

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Institute of Pediatrics, Medical Academy, Poznan, Poland.

Abstract

The reciprocal translocation t(2;17) (q21.2; q23.2) was used to map the human genes for myeloperoxidase (MPO), protein kinase C, alpha polypeptide, PRKCA, and the anonymous DNA fragment D17S21 more precisely on human chromosome 17q. MPO and PRKCA remain on the der(17) chromosome and therefore are assigned to 17(q21.3-q23.2) and 17(q22-q23.2), respectively. D17S21 is translocated to chromosome der(2) and by this is assigned to 17(q23.3-q24).

PMID:: 1663499; [PubMed - indexed for MEDLINE]

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Localization of myeloperoxidase to the long arm of human chromosome 17: relationship to the 15; 17 translocation of acute promyelocytic leukemia. [Oncogene. 1987]
Localization of myeloperoxidase to the long arm of human chromosome 17: relationship to the 15; 17 translocation of acute promyelocytic leukemia.
van Tuinen P, Johnson KR, Ledbetter SA, Nussbaum RL, Rovera G, Ledbetter DH. Oncogene. 1987; 1(3):319-22.
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Weil SC, Rosner GL, Reid MS, Chisholm RL, Lemons RS, Swanson MS, Carrino JJ, Diaz MO, Le Beau MM. Science. 1988 May 6; 240(4853):790-2.
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The myeloperoxidase gene is translocated from chromosome 17 to 15 in a patient with acute promyelocytic leukemia.
Liang JC, Chang KS, Schroeder WT, Freireich EJ, Stass SA, Trujillo JM. Cancer Genet Cytogenet. 1988 Jan; 30(1):103-7.

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Cited by 1 PubMed Central article

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Kofler K, Erdel M, Utermann G, Baier G. Genome Biol. 2002; 3(3):RESEARCH0014. Epub 2002 Feb 27.

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