Curr Opin Genet Dev. 1992 Apr;2(2):299-303.

Sex differentiation: the role of alternative splicing.

Source

Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92186.

Abstract

Sex differentiation in Drosophila is controlled by a regulatory cascade with at least three regulated alternative RNA-processing events. The results of recent work have verified much of the earlier molecular and genetic work in this field and have provided a demonstration that both positive and negative regulatory mechanisms are involved.

PMID:: 1638125; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila. [Science. 1991]
Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila.
Hoshijima K, Inoue K, Higuchi I, Sakamoto H, Shimura Y. Science. 1991 May 10; 252(5007):833-6.
Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila. [Development. 1993]
Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila.
Oliver B, Kim YJ, Baker BS. Development. 1993 Nov; 119(3):897-908.
Molecular genetics of transformer, a genetic switch controlling sexual differentiation in Drosophila. [Dev Genet. 1989]
Molecular genetics of transformer, a genetic switch controlling sexual differentiation in Drosophila.
Belote JM, McKeown M, Boggs RT, Ohkawa R, Sosnowski BA. Dev Genet. 1989; 10(3):143-54.
Review Drosophila sex determination: a cascade of regulated splicing. [Cell. 1989]
Review Drosophila sex determination: a cascade of regulated splicing.
Hodgkin J. Cell. 1989 Mar 24; 56(6):905-6.
Review Sex in flies: the splice of life. [Nature. 1989]
Review Sex in flies: the splice of life.
Baker BS. Nature. 1989 Aug 17; 340(6234):521-4.

See reviews... See all...

Cited by 19 PubMed Central articles

Evolution of sex-specific traits through changes in HOX-dependent doublesex expression. [PLoS Biol. 2011]
Evolution of sex-specific traits through changes in HOX-dependent doublesex expression.
Tanaka K, Barmina O, Sanders LE, Arbeitman MN, Kopp A. PLoS Biol. 2011 Aug; 9(8):e1001131. Epub 2011 Aug 23.
Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq. [Cell Res. 2010]
Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq.
Gan Q, Chepelev I, Wei G, Tarayrah L, Cui K, Zhao K, Chen X. Cell Res. 2010 Jul; 20(7):763-83. Epub 2010 May 4.
Sex-specific expression of alternative transcripts in Drosophila. [Genome Biol. 2006]
Sex-specific expression of alternative transcripts in Drosophila.
McIntyre LM, Bono LM, Genissel A, Westerman R, Junk D, Telonis-Scott M, Harshman L, Wayne ML, Kopp A, Nuzhdin SV. Genome Biol. 2006; 7(8):R79. Epub 2006 Aug 25.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Sex differentiation: the role of alternative splicing.
Sex differentiation: the role of alternative splicing.
Curr Opin Genet Dev. 1992 Apr ;2(2):299-303.

PubMed
Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-...
Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene.
Am J Hum Genet. 2005 Dec ;77(6):1021-33. Epub 2005 Oct 26 .

PubMed
Delayed wallerian degeneration in the central nervous system of Ola mice: an ult...
Delayed wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study.
J Neurol Sci. 1992 Jun ;109(2):140-7.

PubMed
Karyotypic Variation within Clonal Lineages of the Rice Blast Fungus, Magnaporth...
Karyotypic Variation within Clonal Lineages of the Rice Blast Fungus, Magnaporthe grisea.
Appl Environ Microbiol. 1993 Feb ;59(2):585-93.

PubMed
The rapid generation of mutation data matrices from protein sequences.
The rapid generation of mutation data matrices from protein sequences.
Comput Appl Biosci. 1992 Jun ;8(3):275-82.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Sex differentiation: the role of alternative splicing.

Source

Abstract

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 19 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information