Ann Neurol. 2005 Oct;58(4):617-22.

A life course approach to cognitive reserve: a model for cognitive aging and development?

Source

Medical Research Council National Survey of Health and Development, University College London, London. m.richards@ucl.ac.uk

Abstract

The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.

PMID:: 16178025; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Seniors' Health - MedlinePlus Health Information

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Life-span learning: a developmental perspective. [Int J Aging Hum Dev. 2003]
Life-span learning: a developmental perspective.
Thornton JE. Int J Aging Hum Dev. 2003; 57(1):55-76.
Review Cognitive reserve and the neurobiology of cognitive aging. [Ageing Res Rev. 2004]
Review Cognitive reserve and the neurobiology of cognitive aging.
Whalley LJ, Deary IJ, Appleton CL, Starr JM. Ageing Res Rev. 2004 Nov; 3(4):369-82.
Review [Dynamics of cognitive abilities in the course of active lifespan]. [Tijdschr Gerontol Geriatr. 1993]
Review [Dynamics of cognitive abilities in the course of active lifespan].
Cremer R. Tijdschr Gerontol Geriatr. 1993 Feb; 24(1):12-7.
Construct validity of cognitive reserve in a multiethnic cohort: The Northern Manhattan Study. [J Int Neuropsychol Soc. 2009]
Construct validity of cognitive reserve in a multiethnic cohort: The Northern Manhattan Study.
Siedlecki KL, Stern Y, Reuben A, Sacco RL, Elkind MS, Wright CB. J Int Neuropsychol Soc. 2009 Jul; 15(4):558-69.
Ergonomic approach in aging: experimental procedures to assess cognitive and balance impairments. [Riv Eur Sci Med Farmacol. 1996]
Ergonomic approach in aging: experimental procedures to assess cognitive and balance impairments.
Pinto MR, Caterina G, Bianchi A, De Medici S, Postiglione A, Napoli C. Riv Eur Sci Med Farmacol. 1996 Jul-Aug; 18(4):153-6.

See reviews... See all...

Cited by 12 PubMed Central articles

A life course approach to the development of mental skills. [J Gerontol B Psychol Sci Soc S...]
A life course approach to the development of mental skills.
Richards M, Hatch SL. J Gerontol B Psychol Sci Soc Sci. 2011 Jul; 66 Suppl 1:i26-35. Epub 2011 Mar 11.
Occupational exposure to solvents and cognitive performance in the GAZEL cohort: preliminary results. [Dement Geriatr Cogn Disord. 2010]
Occupational exposure to solvents and cognitive performance in the GAZEL cohort: preliminary results.
Berr C, Vercambre MN, Bonenfant S, Manoux AS, Zins M, Goldberg M. Dement Geriatr Cogn Disord. 2010; 30(1):12-9. Epub 2010 Jul 5.
The impact of brain size on pilot performance varies with aviation training and years of education. [J Int Neuropsychol Soc. 2010]
The impact of brain size on pilot performance varies with aviation training and years of education.
Adamson MM, Samarina V, Xiangyan X, Huynh V, Kennedy Q, Weiner M, Yesavage J, Taylor JL. J Int Neuropsychol Soc. 2010 May; 16(3):412-23. Epub 2010 Mar 2.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

A life course approach to cognitive reserve: a model for cognitive aging and dev...
A life course approach to cognitive reserve: a model for cognitive aging and development?
Ann Neurol. 2005 Oct ;58(4):617-22.

PubMed
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) res...
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
Cancer Res. 1992 Jul 15 ;52(14):3857-64.

PubMed
UV irradiation induces homologous recombination genes in the model archaeon, Hal...
UV irradiation induces homologous recombination genes in the model archaeon, Halobacterium sp. NRC-1.
Saline Systems. 2005 Jul 4 ;1:3.

PubMed
Caries-risk-reducing effects of xylitol-containing chewing gum and tablets in co...
Caries-risk-reducing effects of xylitol-containing chewing gum and tablets in confectionery workers in Finland.
Community Dent Health. 1992 Mar ;9(1):3-10.

PubMed
Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobac...
Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis.
J Biol Chem. 2005 Nov 25 ;280(47):38942-7. Epub 2005 Sep 20 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: