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    Nature. 1992 Jun 18;357(6379):563-9.

    Gustducin is a taste-cell-specific G protein closely related to the transducins.

    McLaughlin SK, McKinnon PJ, Margolskee RF.

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    Roche Institute of Molecular Biology, Roche Research Center, Nutley, New Jersey 07110-1199.

    Abstract

    A novel G protein alpha-subunit (alpha-gustducin) has been identified and cloned from taste tissue. alpha-Gustducin messenger RNA is expressed in taste buds of all taste papillae (circumvallate, foliate and fungiform); it is not expressed in non-sensory portions of the tongue, nor is it expressed in the other tissues examined. alpha-Gustducin most closely resembles the transducins (the rod and cone photoreceptor G proteins), suggesting that gustducin's role in taste transduction is analogous to that of transducin in light transduction.

    PMID:
    1608467
    [PubMed - indexed for MEDLINE]

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