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National Jewish Center, Denver, Colorado.
Recent studies indicate that hematopoietic stem cells that provide long-term reconstitution can be separated from more mature hematopoietic cells that provide radioprotection and short-term repopulation. With these findings it is now possible to design assays that will specifically measure long-term repopulating stem cells, as well as to develop culture systems that can be used to analyze the effects of known and putative novel cytokines on their growth and differentiation.
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