My NCBISign In

Display Settings:

Format

Send to:

Choose Destination
    Breast Cancer Res. 2005;7(4):153-62. Epub 2005 May 12.

    Imaging in breast cancer: Single-photon computed tomography and positron-emission tomography.

    Bénard F, Turcotte E.

    Source

    Metabolic and Functional Imaging Center, Clinical Research Center, Centre Hospitalier Universitaire de Sherbrooke, Fleurimont, QC, Canada. francois.benard@usherbrooke.ca

    Abstract

    Although mammography remains a key imaging method for the early detection and screening of breast cancer, the overall accuracy of this test remains low. Several radiopharmaceuticals have been proposed as adjunct imaging methods to characterize breast masses by single-photon-emission computed tomography (SPECT) and positron-emission tomography (PET). Useful in characterizing indeterminate palpable masses and in the detection of axillary metastases, these techniques are insufficiently sensitive to detect subcentimetric tumor deposits. Their role in staging nodal involvement of the axillary areas therefore currently remains limited. Several enzymes and receptors have been targeted for imaging breast cancers with PET. [18F]fluorodeoxyglucose is particularly useful in the detection and staging of recurrent breast cancer and in assessing the response to chemotherapy. Several other ligands targeting proliferative activity, protein synthesis, and hormone and cell-membrane receptors may complement this approach by providing unique information about biological characteristics of breast cancer across primary and metastatic tumor sites.

    PMID:
    15987467
    [PubMed - indexed for MEDLINE]
    PMCID: PMC1175073
    Free PMC Article

    Images from this publication.See all images (2) Free text

    Figure 1
    Figure 2

    Publication Types, MeSH Terms, Substances

    Publication Types

    MeSH Terms

    Substances

    LinkOut - more resources

    Full Text Sources

    Other Literature Sources

    Medical

    Libraries

      Supplemental Content

      Click here to read Click here to read

      Related citations

      See reviews... See all...

      Cited by 9 PubMed Central articles

      • Breast imaging: A survey. [World J Clin Oncol. 2011]
        Breast imaging: A survey.
        Sree SV, Ng EY, Acharya RU, Faust O. World J Clin Oncol. 2011 Apr 10; 2(4):171-8.
      • Review 18F-FDG PET/CT imaging in oncology. [Ann Saudi Med. 2011]
        Review 18F-FDG PET/CT imaging in oncology.
        Almuhaideb A, Papathanasiou N, Bomanji J. Ann Saudi Med. 2011 Jan-Feb; 31(1):3-13.
      • Modern breast cancer detection: a technological review. [Int J Biomed Imaging. 2009]
        Modern breast cancer detection: a technological review.
        Nover AB, Jagtap S, Anjum W, Yegingil H, Shih WY, Shih WH, Brooks AD. Int J Biomed Imaging. 2009; 2009:902326. Epub 2009 Dec 28.
      See all...

      Related information

      • Related Citations
        Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
      • Compound (MeSH Keyword)
        PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
      • References for this PMC Article
        Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
      • Substance (MeSH Keyword)
        PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
      • Free in PMC
        Free full text articles in PMC
      • Cited in PMC
        Full-text articles in the PubMed Central Database that cite the current articles.

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      You are here: NCBI > Literature > PubMed
      Write to the Help Desk