Science. 1992 May 1;256(5057):673-5.

Occurrence of sialic acids in Drosophila melanogaster.

Roth J, Kempf A, Reuter G, Schauer R, Gehring WJ.

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Department of Cell Biology, University of Basel, Switzerland.

Abstract

Sialylated oligosaccharides, which are cell type-specific and developmentally regulated, have been implicated in a variety of complex biological events. Their broad functional importance is reflected by their presence in a wide variety of phyla extending from Echinodermata through higher vertebrates. Here, sialic acids are detected throughout development in an insect, Drosophila. Homopolymers of alpha 2,8-linked sialic acid, polysialic acid, are developmentally regulated and only expressed during early Drosophila development.

PMID:: 1585182; [PubMed - indexed for MEDLINE]

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[A highly sialylated, embryonic form of the neural cell adhesion molecule in Wilms tumor: identification of a cell adhesion molecule as a onco-developmental antigen]. [Verh Dtsch Ges Pathol. 1989]
[A highly sialylated, embryonic form of the neural cell adhesion molecule in Wilms tumor: identification of a cell adhesion molecule as a onco-developmental antigen].
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