Curr Opin Cell Biol. 2005 Apr;17(2):223-9.

Cellular oscillators: rhythmic gene expression and metabolism.

Source

Department of Molecular Biology and NCCR Frontiers in Genetics, Sciences III, University of Geneva, 30, Quai Ernest Ansermet, CH-1211 Geneva-4, Switzerland. Ueli.Schibler@molbio.unige.ch

Abstract

Many biological processes are driven by biological clocks that, depending on the frequency they generate, are classified into ultradian, circadian and infradian oscillators. In virtually all light-sensitive organisms from cyanobacteria to humans, a circadian timing system adapts cyclic physiology to geophysical time. Recent evidence suggests that even in mammals circadian oscillators function in a cell-autonomous manner. In yeast, an ultradian oscillator regulates cyclic respiratory activity and global gene expression. Circadian oscillators and the ultradian yeast respiratory clock share at least four properties: they follow limit-cycle kinetics, interweave with cellular metabolism, are temperature-compensated and influence the cell division clock.

PMID:: 15780601; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Cell Cycle Proteins

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Saccharomyces Genome Database

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Review Circadian time keeping: the daily ups and downs of genes, cells, and organisms. [Prog Brain Res. 2006]
Review Circadian time keeping: the daily ups and downs of genes, cells, and organisms.
Schibler U. Prog Brain Res. 2006; 153:271-82.
Review Properties, entrainment, and physiological functions of mammalian peripheral oscillators. [J Biol Rhythms. 2006]
Review Properties, entrainment, and physiological functions of mammalian peripheral oscillators.
Stratmann M, Schibler U. J Biol Rhythms. 2006 Dec; 21(6):494-506.
Impact of behavior on central and peripheral circadian clocks in the common vole Microtus arvalis, a mammal with ultradian rhythms. [Proc Natl Acad Sci U S A. 2006]
Impact of behavior on central and peripheral circadian clocks in the common vole Microtus arvalis, a mammal with ultradian rhythms.
van der Veen DR, Minh NL, Gos P, Arneric M, Gerkema MP, Schibler U. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3393-8. Epub 2006 Feb 15.
Resilient circadian oscillator revealed in individual cyanobacteria. [Nature. 2004]
Resilient circadian oscillator revealed in individual cyanobacteria.
Mihalcescu I, Hsing W, Leibler S. Nature. 2004 Jul 1; 430(6995):81-5.
Review A time to fast, a time to feast: the crosstalk between metabolism and the circadian clock. [Mol Cells. 2009]
Review A time to fast, a time to feast: the crosstalk between metabolism and the circadian clock.
Kovac J, Husse J, Oster H. Mol Cells. 2009 Aug 31; 28(2):75-80. Epub 2009 Aug 20.

See reviews... See all...

Cited by 21 PubMed Central articles

Intrinsic noise alters the frequency spectrum of mesoscopic oscillatory chemical reaction systems. [Sci Rep. 2011]
Intrinsic noise alters the frequency spectrum of mesoscopic oscillatory chemical reaction systems.
Ramaswamy R, Sbalzarini IF. Sci Rep. 2011; 1:154. Epub 2011 Nov 11.
Critical self-organized self-sustained oscillations in large regulatory networks: towards understanding the gene expression initiation. [Gene Regul Syst Bio. 2011]
Critical self-organized self-sustained oscillations in large regulatory networks: towards understanding the gene expression initiation.
Rosenfeld S. Gene Regul Syst Bio. 2011 Mar 22; 5:27-40. Epub 2011 Mar 22.
Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver. [PLoS Biol. 2011]
Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver.
Rey G, Cesbron F, Rougemont J, Reinke H, Brunner M, Naef F. PLoS Biol. 2011 Feb; 9(2):e1000595. Epub 2011 Feb 22.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cellular oscillators: rhythmic gene expression and metabolism.
Cellular oscillators: rhythmic gene expression and metabolism.
Curr Opin Cell Biol. 2005 Apr ;17(2):223-9.

PubMed
Prevention of nosocomial pneumonia in intubated patients: respective role of mec...
Prevention of nosocomial pneumonia in intubated patients: respective role of mechanical subglottic secretions drainage and stress ulcer prophylaxis.
Intensive Care Med. 1992 ;18(1):20-5.

PubMed
Malaria vectors and urbanization in the equatorial forest region of south Camero...
Malaria vectors and urbanization in the equatorial forest region of south Cameroon.
Trans R Soc Trop Med Hyg. 2005 May ;99(5):347-54.

PubMed
Topographical organization and relationship with ventral striatal compartments o...
Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat.
J Comp Neurol. 1992 Feb 15 ;316(3):314-47.

PubMed
Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacte...
Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacter.
Proc Natl Acad Sci U S A. 2002 Dec 24 ;99(26):17049-54. Epub 2002 Dec 16 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: