J Pediatr Orthop. 1992 May-Jun;12(3):398-400.

Chronic granulomatous disease presenting with osteomyelitis: favorable response to treatment with interferon-gamma.

Gill PJ, Goddard E, Beatty DW, Hoffman EB.

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Department of Orthopaedic Surgery, University of Cape Town, Red Cross Children's Hospital, South Africa.

Abstract

A 3-year-old boy with chronic granulomatous disease presented with abscesses related to underlying osteomyelitis. Treatment with appropriate antibiotics resulted in resistance of the organisms. Treatment with interferon-gamma was encouraging in that it caused the osteomyelitis to heal and prevented its relapse when used as long-term prophylaxis.

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