Cerebrospinal Fluid Res. 2004 Dec 10;1(1):5.

Epidemiology of neural tube defects and folic acid.

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Department of Pediatrics, University of Washington, Seattle, WA 98105, USA. David.Shurtleff@seattlechildrens.org.

Abstract

This review article combines four disparate observations about Neural Tube Defects (NTDs). They are the worldwide decline in the birth incidence that began prior to prenatal diagnosis; family recurrence risks; the effect of prenatal diagnosis and termination of affected pregnancies; and the effect of folic acid.

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PMCID: PMC546400

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Epidemiology of neural tube defects and folic acid.

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