Nutrition. 1992 Jan-Feb;8(1):37-40.

Histopathology of essential fatty acid-deficient mice.

Eynard AR, Cejas V, Silva R, Quiroga P, Muñoz S.

Source

II Catedra de Histologia, FCM-Universidad Nacional de Cordoba, Argentina.

Abstract

This histological study reports the pathological findings in mice deficient in essential fatty acids (EFAD). As shown by others, hyperplasia and hyperkeratosis were observed in skin. In addition, we reported hyperkeratosis of the esophagus and forestomach, severe degrees of atrophy of the seminal epithelium of testes, and diminution of the luminal content of epididymis, and the formation of clusters of lipid-laden macrophages in lungs. Hyperemia was also a systemic change in many organs. These alterations have not been reported in EFAD mice previously.

PMID:: 1562787; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Fatty Acids, Essential

LinkOut - more resources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies). [Natl Toxicol Program Tech Rep ...]
NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 1996 Aug; 383:1-370.
NTP Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate (CAS No. 10101-97-0) in F344 Rats and B6C3F1 Mice (Inhalation Studies). [Natl Toxicol Program Tech Rep ...]
NTP Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate (CAS No. 10101-97-0) in F344 Rats and B6C3F1 Mice (Inhalation Studies).
National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 1996 Jul; 454:1-380.
Effects of vitamin D in lung, stomach, esophagus and testis tissues following administration of urethane in balb/c mice. [Saudi Med J. 2008]
Effects of vitamin D in lung, stomach, esophagus and testis tissues following administration of urethane in balb/c mice.
Koohdani F, Baghdadchi J, Sasani F, Mohammad K, Mehdipour P. Saudi Med J. 2008 Mar; 29(3):340-4.
Review Intestinal absorption of essential fatty acids under physiological and essential fatty acid-deficient conditions. [J Lipid Res. 1997]
Review Intestinal absorption of essential fatty acids under physiological and essential fatty acid-deficient conditions.
Minich DM, Vonk RJ, Verkade HJ. J Lipid Res. 1997 Sep; 38(9):1709-21.
Review The essentiality of arachidonic acid and docosahexaenoic acid. [Prostaglandins Leukot Essent F...]
Review The essentiality of arachidonic acid and docosahexaenoic acid.
Le HD, Meisel JA, de Meijer VE, Gura KM, Puder M. Prostaglandins Leukot Essent Fatty Acids. 2009 Aug-Sep; 81(2-3):165-70. Epub 2009 Jun 18.

See reviews... See all...

Cited by 1 PubMed Central article

Mechanisms of lipid malabsorption in Cystic Fibrosis: the impact of essential fatty acids deficiency. [Nutr Metab (Lond). 2005]
Mechanisms of lipid malabsorption in Cystic Fibrosis: the impact of essential fatty acids deficiency.
Peretti N, Marcil V, Drouin E, Levy E. Nutr Metab (Lond). 2005 May 3; 2(1):11. Epub 2005 May 3.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Histopathology of essential fatty acid-deficient mice.
Histopathology of essential fatty acid-deficient mice.
Nutrition. 1992 Jan-Feb ;8(1):37-40.

PubMed
Fuel utilization in subjects with carnitine palmitoyltransferase 2 gene mutation...
Fuel utilization in subjects with carnitine palmitoyltransferase 2 gene mutations.
Ann Neurol. 2005 Jan ;57(1):60-6.

PubMed
Quantification of adipose tissue by MRI: relationship with anthropometric variab...
Quantification of adipose tissue by MRI: relationship with anthropometric variables.
J Appl Physiol. 1992 Feb ;72(2):787-95.

PubMed
Increased oxidative stress in obesity and its impact on metabolic syndrome.
Increased oxidative stress in obesity and its impact on metabolic syndrome.
J Clin Invest. 2004 Dec ;114(12):1752-61.

PubMed
Use of multi-frequency bioelectrical impedance analysis for the estimation of ex...
Use of multi-frequency bioelectrical impedance analysis for the estimation of extracellular fluid.
Eur J Clin Nutr. 1992 Feb ;46(2):117-24.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: