Nucleic Acids Res. 1992 Mar 25;20(6):1387-91.

A protein which specifically binds to single stranded TTAGGGn repeats.

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Medical Research Council Human Genetics Unit, Western General Hospital, Edinburgh, UK.

Abstract

Nuclei from tissues of many vertebrates contain a soluble 37 kd protein which binds with a high degree of specificity to oligonucleotides which contain the G rich strand of the telomeric terminal repeats, TTAGGG. In some tissues this is an abundant nuclear protein.

PMID:: 1561094; [PubMed - indexed for MEDLINE]
PMCID:: PMC312187

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