Sleep. 1992 Aug;15(4):330-6.

Sleep propensity free-runs with the temperature, melatonin and cortisol rhythms in a totally blind person.

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Department of Psychiatry, School of Medicine, Oregon Health Sciences University, Portland 97201.

Abstract

In previous studies, we found that many totally blind people have free-running melatonin rhythms, but that free-running melatonin rhythms were not necessarily associated with periodic insomnia and daytime sleepiness. Thus, it was not clear if the circadian sleep propensity rhythm was free-running with the other circadian rhythms. In the present study, we report that the sleep propensity rhythm (as defined by an ultrashort sleep-wake schedule) free-ran with the melatonin, temperature and cortisol rhythms in a 44-year-old totally blind man even though he maintained a conventional sleep schedule and did not complain of clinically significant insomnia or excessive daytime sleepiness.

PMID:: 1519008; [PubMed - indexed for MEDLINE]

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