Childs Nerv Syst. 2004 Jul;20(7):468-72. Epub 2004 May 12.

Cerebral toxocariasis: a possible cause of epileptic seizure in children.

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Department of Neurosurgery, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland. hbaechli@uhbs.ch

Abstract

INTRODUCTION:

Toxocariasis is a worldwide human helminthiasis, which is mostly asymptomatic and caused by toxocara canis, a roundworm in dogs. These can cause visceral larva migrans syndrome in humans who ingest contaminated soil. CNS manifestation with a focal mass lesion is very rare, seizures often being the first symptom.

CASE REPORT:

We describe an 11-year-old girl presenting with a generalized epileptic seizure and eosinophilia in blood. Under antibiotic therapy under the assumption of toxoplasmosis the lesion did not decrease and surgical resection was considered. We used computer-assisted surgery (CAS) for careful tissue resection. Postoperatively the diagnosis of toxocariasis was confirmed and albendozole medication was administered for 7 days. The patient developed well without neurological deficits or seizures.

CONCLUSION:

We conclude that although neurological involvement is rare in toxocariasis, a cerebral infection in a child with epileptic seizures and eosinophilia should be considered.

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[Cerebral vasculitis secondary to Toxocara canis and Fasciola hepatica co-infestation]. [Rev Neurol (Paris). 2003]
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Cited by 3 PubMed Central articles

Recurrent cerebral larva migrans: A case report and review of literature. [J Pediatr Neurosci. 2009]
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Jagannath PM, Venkataramana NK, Rao SA, Naik AL, Shivakumar SK, Saktepar A, Gopalakrishnan R, Shankar SK. J Pediatr Neurosci. 2009 Jan; 4(1):36-40.
Serological studies of neurologic helminthic infections in rural areas of southwest cameroon: toxocariasis, cysticercosis and paragonimiasis. [PLoS Negl Trop Dis. 2010]
Serological studies of neurologic helminthic infections in rural areas of southwest cameroon: toxocariasis, cysticercosis and paragonimiasis.
Nkouawa A, Sako Y, Itoh S, Kouojip-Mabou A, Nganou CN, Saijo Y, Knapp J, Yamasaki H, Nakao M, Nakaya K, et al. PLoS Negl Trop Dis. 2010 Jul 6; 4(7):e732. Epub 2010 Jul 6.
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Cerebral toxocariasis: a possible cause of epileptic seizure in children.
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Cerebral toxocariasis: a possible cause of epileptic seizure in children.

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Abstract

INTRODUCTION:

CASE REPORT:

CONCLUSION:

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