Science. 2004 Mar 12;303(5664):1626-32.

Mobile elements: drivers of genome evolution.

Source

Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. kazazian@mail.med.upenn.edu

Abstract

Mobile elements within genomes have driven genome evolution in diverse ways. Particularly in plants and mammals, retrotransposons have accumulated to constitute a large fraction of the genome and have shaped both genes and the entire genome. Although the host can often control their numbers, massive expansions of retrotransposons have been tolerated during evolution. Now mobile elements are becoming useful tools for learning more about genome evolution and gene function.

PMID:: 15016989; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Review Mobile genetic elements as natural tools for genome evolution. [Methods Mol Biol. 2004]
Review Mobile genetic elements as natural tools for genome evolution.
Miller WJ, Capy P. Methods Mol Biol. 2004; 260:1-20.
Genetics. L1 retrotransposons shape the mammalian genome. [Science. 2000]
Genetics. L1 retrotransposons shape the mammalian genome.
Kazazian HH Jr. Science. 2000 Aug 18; 289(5482):1152-3.
Review [Non-LTR retrotransposons: LINEs and SINEs in plant genome]. [Yi Chuan. 2006]
Review [Non-LTR retrotransposons: LINEs and SINEs in plant genome].
Cheng XD, Ling HQ. Yi Chuan. 2006 Jun; 28(6):731-6.
Nonmethylated transposable elements and methylated genes in a chordate genome. [Science. 1999]
Nonmethylated transposable elements and methylated genes in a chordate genome.
Simmen MW, Leitgeb S, Charlton J, Jones SJ, Harris BR, Clark VH, Bird A. Science. 1999 Feb 19; 283(5405):1164-7.
Review Interspersed repeats and other mementos of transposable elements in mammalian genomes. [Curr Opin Genet Dev. 1999]
Review Interspersed repeats and other mementos of transposable elements in mammalian genomes.
Smit AF. Curr Opin Genet Dev. 1999 Dec; 9(6):657-63.

See reviews... See all...

Cited by over 100 PubMed Central articles

Intrinsic restriction activity by AID/APOBEC family of enzymes against the mobility of retroelements. [Mob Genet Elements. 2011]
Intrinsic restriction activity by AID/APOBEC family of enzymes against the mobility of retroelements.
Koito A, Ikeda T. Mob Genet Elements. 2011 Sep; 1(3):197-202. Epub 2011 Sep 1.
Transposable elements are a major cause of somatic polymorphism in Vitis vinifera L. [PLoS One. 2012]
Transposable elements are a major cause of somatic polymorphism in Vitis vinifera L.
Carrier G, Le Cunff L, Dereeper A, Legrand D, Sabot F, Bouchez O, Audeguin L, Boursiquot JM, This P. PLoS One. 2012; 7(3):e32973. Epub 2012 Mar 12.
PCR and magnetic bead-mediated target capture for the isolation of short interspersed nucleotide elements in fishes. [Int J Mol Sci. 2012]
PCR and magnetic bead-mediated target capture for the isolation of short interspersed nucleotide elements in fishes.
Liu D, Zhu G, Tang W, Yang J, Guo H. Int J Mol Sci. 2012; 13(2):2048-62. Epub 2012 Feb 15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Mobile elements: drivers of genome evolution.
Mobile elements: drivers of genome evolution.
Science. 2004 Mar 12 ;303(5664):1626-32.

PubMed
Characterisation of the secretory acetylcholinesterases from adult Nippostrongyl...
Characterisation of the secretory acetylcholinesterases from adult Nippostrongylus brasiliensis.
Mol Biochem Parasitol. 1992 Jul ;53(1-2):79-88.

PubMed
GeneWays: a system for extracting, analyzing, visualizing, and integrating molec...
GeneWays: a system for extracting, analyzing, visualizing, and integrating molecular pathway data.
J Biomed Inform. 2004 Feb ;37(1):43-53.

PubMed
DNA fingerprinting of Escherichia coli O157:H7 strains by pulsed-field gel elect...
DNA fingerprinting of Escherichia coli O157:H7 strains by pulsed-field gel electrophoresis.
J Clin Microbiol. 1992 Aug ;30(8):2169-72.

PubMed
Proof and evolutionary analysis of ancient genome duplication in the yeast Sacch...
Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae.
Nature. 2004 Apr 8 ;428(6983):617-24. Epub 2004 Mar 7 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: