Agents Actions. 1992 Sep;37(1-2):155-6.

The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells.

Yasui T, Akatsuka M, Tobetto K, Hayaishi M, Ando T.

Source

Division of Biochemical Pharmacology, Maruho Co., Ltd, Osaka, Japan.

Abstract

An in vitro study on the effects of hyaluronan (HA) on interleukin-1 alpha-induced prostaglandin E2 (PGE2) production in human osteoarthritic synovial cells indicated that PGE2 induction was suppressed by HA in a dose- and molecular weight-dependent manner.

PMID:: 1456177; [PubMed - indexed for MEDLINE]

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Cited by 4 PubMed Central articles

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