Science. 1963 May 31;140(3570):976-8.

Mammalian X-chromosome action: inactivation limited in spread and region of origin.

Abstract

In its simplest form the hypothesis of the single-active-X chromosome does not explain variegated-type position effects in the mouse. Inactivity appears not to involve one entire X chromosome; furthermore, even those parts of the chromosome that can change to an inactive state spread inactivation not to the entire attached piece of autosome, but along a gradient to limited distances.

PMID:: 13975649; [PubMed - indexed for MEDLINE]

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Some insights into X chromosome inactivation from studies of human cells. [Ann Endocrinol (Paris). 1980]
Some insights into X chromosome inactivation from studies of human cells.
Migeon BR. Ann Endocrinol (Paris). 1980 Jul-Aug; 41(4):275-80.
Inactivation system of the mammalian X chromosome. [Proc Natl Acad Sci U S A. 1973]
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Monk M. J Inherit Metab Dis. 1992; 15(4):499-513.
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Mammalian X-chromosome action: inactivation limited in spread and region of origin.

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