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Tumor Hospital, Zhongshan Medical University, Guangzhou, Guangdong.
137 cases of nasopharyngeal carcinoma were treated by photodynamic therapy (PDT). Forty-eight and 72 hours after iv administration of 3-5 mg/kg HpD, laser treatment with either argon or dye laser was given. Dye laser (630 nm) with over 350 mw output transmitted through quartz fiber was given to 57 patients. Argon laser (488 nm and 514.5 nm) was delivered to 80 patients. The results were: complete response 76 cases (55.47%) and marked response 47 cases (34.31%), with an over-all marked response rate of 89.78% (123/137). The efficacy and indication of photodynamic therapy for nasopharyngeal carcinoma using various light sources (argon and dye laser) are discussed.
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