Curr Opin Biotechnol. 1991 Dec;2(6):818-22.

Genetic marker technology.

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Institute for Molecular, Baylor College of Medicine, Houston, Texas.

Abstract

Advances in our understanding of polymorphisms found in eukaryotic genomes and improved methods for studying genetic markers should facilitate genetic linkage mapping and other applications. Progress within the past year includes characterization of the types, frequencies, and properties of tandemly repeated sequences, methods for obtaining the DNA sequence flanking genetic markers for use in the polymerase chain reaction, and new detection systems featuring automation and multiplexing.

PMID:: 1367954; [PubMed - indexed for MEDLINE]

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