Cleve Clin J Med. 2003 May;70(5):389, 392-3, 397 passim.

When to wean from a ventilator: an evidence-based strategy.

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Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain.

Abstract

It is often unclear when and how to wean patients from mechanical ventilation. We have devised an evidence-based protocol in which patients undergo a 30-minute trial of spontaneous breathing with a T tube or pressure support of 7 cm H2O. Those who can tolerate the trial are extubated, while those who cannot are reconnected to mechanical ventilation but undergo another trial every day until they can be extubated. More study is needed to improve the criteria to predict successful spontaneous breathing and extubation, and to clarify the role of non-invasive ventilation to avoid reintubation.

PMID:: 12779129; [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation. [Clinics (Sao Paulo). 2009]
Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation.
Rieder Mde M, Costa AD, Vieira SR. Clinics (Sao Paulo). 2009 May; 64(5):403-8.
Prediction of extubation outcome: a randomised, controlled trial with automatic tube compensation vs. pressure support ventilation. [Crit Care. 2009]
Prediction of extubation outcome: a randomised, controlled trial with automatic tube compensation vs. pressure support ventilation.
Cohen J, Shapiro M, Grozovski E, Fox B, Lev S, Singer P. Crit Care. 2009; 13(1):R21. Epub 2009 Feb 23.

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