Arthritis Res. 2002;4(4):247-51. Epub 2002 Jan 31.

Genetic epidemiology. Psoriatic arthritis.

Source

Arthritis Rheumatism Campaign Epidemiology Research Unit, University of Manchester, UK. ABarton@fs1.ser.man.ac.uk

Abstract

The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis. However, a distinct entity is likely to have distinct susceptibility factors in addition to those that contribute to psoriasis and inflammatory arthritis alone. These aetiological factors may be genetic and/or environmental, and in this review, the evidence for distinct psoriatic arthritis genetic susceptibility factors is considered.

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