Genome Biol. 2002;3(3):REVIEWS0004. Epub 2002 Feb 28.

Untranslated regions of mRNAs.

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Dipartimento di Fisiologia e Biochimica Generali, Università di Milano, Via Celoria, 26, 20133 Milano, Italy. graziano.pesole@unimi.it

Abstract

Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.

PMID:: 11897027; [PubMed - indexed for MEDLINE]
PMCID: PMC139023

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