Bull Entomol Res. 2001 Aug;91(4):265-72.

Bioassay and biochemical analyses of insecticide resistance in southern African Anopheles funestus (Diptera: Culicidae).

Brooke BD, Kloke G, Hunt RH, Koekemoer LL, Temu EA, Taylor ME, Small G, Hemingway J, Coetzee M.

Source

Medical Entomology, Department of Clinical Microbiology and Infectious Diseases, School of Pathology of the South African Institute for Medical Research, Johannesburg, 2000, South Africa. basilb@mail.saimr.wits.ac.za

Abstract

Anopheles funestus Giles has been implicated as a major malaria vector in sub-Saharan Africa where pyrethroid insecticides are widely used in agriculture and public health. Samples of this species from northern Kwazulu/Natal in South Africa and the Beluluane region of southern Mozambique showed evidence of resistance to pyrethroid insecticides. Insecticide exposure, synergist and biochemical assays conducted on A. funestus suggested that elevated levels of mixed function oxidases were responsible for the detoxification of pyrethroids in resistant mosquitoes in these areas. The data suggested that this mechanism was also conferring cross-resistance to the carbamate insecticide propoxur.

PMID:: 11587622; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Libraries

LinkOut Holdings

Supplemental Content

Related citations

Insecticide resistance in Anopheles funestus (Diptera: Culicidae) from Mozambique. [J Med Entomol. 2006]
Insecticide resistance in Anopheles funestus (Diptera: Culicidae) from Mozambique.
Casimiro S, Coleman M, Mohloai P, Hemingway J, Sharp B. J Med Entomol. 2006 Mar; 43(2):267-75.
Indoor collections of the Anopheles funestus group (Diptera: Culicidae) in sprayed houses in northern KwaZulu-Natal, South Africa. [Malar J. 2007]
Indoor collections of the Anopheles funestus group (Diptera: Culicidae) in sprayed houses in northern KwaZulu-Natal, South Africa.
Mouatcho JC, Hargreaves K, Koekemoer LL, Brooke BD, Oliver SV, Hunt RH, Coetzee M. Malar J. 2007 Mar 14; 6:30. Epub 2007 Mar 14.
Anopheles arabiensis and An. quadriannulatus resistance to DDT in South Africa. [Med Vet Entomol. 2003]
Anopheles arabiensis and An. quadriannulatus resistance to DDT in South Africa.
Hargreaves K, Hunt RH, Brooke BD, Mthembu J, Weeto MM, Awolola TS, Coetzee M. Med Vet Entomol. 2003 Dec; 17(4):417-22.
Review Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control? [Trends Parasitol. 2011]
Review Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?
Ranson H, N'guessan R, Lines J, Moiroux N, Nkuni Z, Corbel V. Trends Parasitol. 2011 Feb; 27(2):91-8. Epub 2010 Sep 16.
Review Insecticide treated nets: impact on vector populations and relevance of initial intensity of transmission and pyrethroid resistance. [J Vector Borne Dis. 2003]
Review Insecticide treated nets: impact on vector populations and relevance of initial intensity of transmission and pyrethroid resistance.
Curtis CF, Jana-Kara B, Maxwell CA. J Vector Borne Dis. 2003 Mar-Jun; 40(1-2):1-8.

See reviews... See all...

Cited by 27 PubMed Central articles

Exploring mechanisms of multiple insecticide resistance in a population of the malaria vector Anopheles funestus in Benin. [PLoS One. 2011]
Exploring mechanisms of multiple insecticide resistance in a population of the malaria vector Anopheles funestus in Benin.
Djouaka R, Irving H, Tukur Z, Wondji CS. PLoS One. 2011; 6(11):e27760. Epub 2011 Nov 16.
Reduction in host-finding behaviour in fungus-infected mosquitoes is correlated with reduction in olfactory receptor neuron responsiveness. [Malar J. 2011]
Reduction in host-finding behaviour in fungus-infected mosquitoes is correlated with reduction in olfactory receptor neuron responsiveness.
George J, Blanford S, Domingue MJ, Thomas MB, Read AF, Baker TC. Malar J. 2011 Aug 3; 10:219. Epub 2011 Aug 3.
The emergence of insecticide resistance in central Mozambique and potential threat to the successful indoor residual spraying malaria control programme. [Malar J. 2011]
The emergence of insecticide resistance in central Mozambique and potential threat to the successful indoor residual spraying malaria control programme.
Abilio AP, Kleinschmidt I, Rehman AM, Cuamba N, Ramdeen V, Mthembu DS, Coetzer S, Maharaj R, Wilding CS, Steven A, et al. Malar J. 2011 May 2; 10:110. Epub 2011 May 2.

See all...

Chemical compound information

cyhalothrin

MW: 449.85 g/mol

MF: C₂₃H₁₉ClF₃NO₃

See 6 citations for this compound....

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Bioassay and biochemical analyses of insecticide resistance in southern African ...
Bioassay and biochemical analyses of insecticide resistance in southern African Anopheles funestus (Diptera: Culicidae).
Bull Entomol Res. 2001 Aug ;91(4):265-72.

PubMed
Malaria in U.S. military forces: a description of deployment exposures from 2003...
Malaria in U.S. military forces: a description of deployment exposures from 2003 through 2005.
Am J Trop Med Hyg. 2007 Feb ;76(2):275-9.

PubMed
Dynamics of P. falciparum gametocytemia in symptomatic patients in an area of in...
Dynamics of P. falciparum gametocytemia in symptomatic patients in an area of intense perennial transmission in Tanzania.
Am J Trop Med Hyg. 2000 Sep-Oct ;63(3-4):199-203.

PubMed
Atovaquone-proguanil for treating uncomplicated malaria.
Atovaquone-proguanil for treating uncomplicated malaria.
Cochrane Database Syst Rev. 2005 Oct 19 ;(4):CD004529.

PubMed
Factors contributing to delay in parasite clearance in uncomplicated falciparum ...
Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children.
Malar J. 2010 Feb 15 ;9:53.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Bioassay and biochemical analyses of insecticide resistance in southern African Anopheles funestus (Diptera: Culicidae).

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Libraries

Supplemental Content

Related citations

Cited by 27 PubMed Central articles

Chemical compound information

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information