FEBS Lett. 1975 Aug 15;56(2):303-6.

[Competitive inhibition of Phe: tRNA ligase of sheep embryos by aurintricarboxylic acid].

[Article in French]

Abstract

Aurin tricarboxylic acid (A.T.A.), an inhibitor of protein biosynthesis (initiation and elongation steps), acts also as a competitive inhibitor of phenylalanine, in the ATP-PPi exchange and tRNAPhe aminoacylation reactions catalysed by cytoplasmic wheat germ phenylalanine:tRNA ligase.

PMID:: 1157948; [PubMed - indexed for MEDLINE]

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